Synthetic Biology Of Non-ribosomal Peptide Synthetases To Generate New Peptides

  Address - Germany

  Contact details - 565656565

  Tender notice no. - 76454545

  MT Ref Id - 10090887

  Document Type - Tender Notices

Description - Status : Grant agreement signedOverall budget : € 3 165 788EU contribution : € 3 165 788Natural products (nps) generated by microbial non-ribosomal peptide synthetases (nrps) represent several very important and valuable clinical antibiotics, imm une-suppressive and anti-cancer drugs. Nps have gone on to inspire several synthetic peptides that are used clinically, but contain amino acids (aas) or other building blocks that are not found in nature. However, with >500 identified aas and additional peptide modifications like glycosylation or cyclization, the chemical diversity in nrps-derived peptides is far larger than proteins and has not yet been fully explored. The modular nature of nrps

Mt Ref Id - 10090887

Deadline - Sep 30, 2024